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1

Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors

Goel, Shom, Wang, Qi, Watt, April C., Tolaney, Sara M., Dillon, Deborah A., Li, Wei, Ramm, Susanne, Palmer, Adam C., Yuzugullu, Haluk, Varadan, Vinay, Tuck, David, Harris, Lyndsay N., Wong, Kwok-Kin,

Journal:

Year:

2016

Language:

english

File:

PDF, 6.28 MB

english, 2016

2

An efficient synthesis of (E)-(2-arylpyrazino[1,2-a]pyrimidine-4-ylidene)acetonitriles and cyanomethyl appended pyrimidines

Ramendra Pratap, Shom Prakash Kushwaha, Atul Goel, Vishnu Ji Ram

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 158 KB

english, 2007

3

Guanidine and amidine mediated synthesis of bridgehead triazaphenalenes, pyrimidines and pyridines through domino reactions

Ramendra Pratap, Abhijeet Deb Roy, Shom Prakash Kushwaha, Atul Goel, Raja Roy, Vishnu Ji Ram

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

4

Morphological changes and stress responses in neurons in cerebral cortex infiltrated by diffuse astrocytoma

Shom Goel, Stephen B. Wharton, Laurence P. Brett, Ian R. Whittle

Journal:

Year:

2003

Language:

english

File:

PDF, 391 KB

english, 2003

5

Phase II study of gemcitabine and docetaxel in combination for the treatment of metastatic breast cancer

Shom GOEL, Ehtesham ABDI, Craig R LEWIS, Matthew LINKS, Steven BEGBIE, Philip CLINGAN, Vinod GANJU, Jane BEITH

Journal:

Asia-Pacific Journal of Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 138 KB

english, 2009

6

Cancer drugs in the real world

Shom GOEL, Anne HAMILTON

Journal:

Asia-Pacific Journal of Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

7

Exploratory analysis of cardiac biomarkers in women with normal cardiac function receiving trastuzumab for breast cancer

Shom Goel, R John Simes, Jane M Beith

Journal:

Asia-Pacific Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 92 KB

english, 2011

8

Rational use of trastuzumab in metastatic and locally advanced breast cancer: Implications of recent research

Shom Goel, Jacquie Chirgwin, Prudence Francis, Robin Stuart-Harris, Joanna Dewar, Linda Mileshkin, Ray Snyder, Michael Michael, Bogda Koczwara

Journal:

Year:

2011

Language:

english

File:

PDF, 195 KB

english, 2011

9

Cochrane Database of Systematic Reviews (Protocols) || LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women

Year:

1996

Language:

english

File:

PDF, 403 KB

english, 1996

10

Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients

Tolaney, Sara M., Boucher, Yves, Duda, Dan G., Martin, John D., Seano, Giorgio, Ancukiewicz, Marek, Barry, William T., Goel, Shom, Lahdenrata, Johanna, Isakoff, Steven J., Yeh, Eren D., Jain, Saloni R

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 871 KB

english, 2015

11

Optimizing the Management of Metastatic HER2-Positive Breast Cancer

Goel, Shom, Tolaney, Sara

Journal:

Current Breast Cancer Reports

Year:

2015

Language:

english

File:

PDF, 859 KB

english, 2015

12

Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

Sachie Hiratsuka, Shom Goel, Walid S. Kamoun, Yoshiro Maru, Dai Fukumura, Dan G. Duda and Rakesh K. Jain

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

13

C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells

Sachie Hiratsuka, Dan G. Duda, Yuhui Huang, Shom Goel, Tatsuki Sugiyama, Takashi Nagasawa, Dai Fukumura and Rakesh K. Jain

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.73 MB

english, 2011

14

Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases

Ni, Jing, Ramkissoon, Shakti H, Xie, Shaozhen, Goel, Shom, Stover, Daniel G, Guo, Hanbing, Luu, Victor, Marco, Eugenio, Ramkissoon, Lori A, Kang, Yun Jee, Hayashi, Marika, Nguyen, Quang-De, Ligon, Azr

Journal:

Nature Medicine

Year:

2016

Language:

english

File:

PDF, 1.09 MB

english, 2016

15

PIK3CA mutations in HER2-positive breast cancer - an ongoing conundrum

Goel, Shom, Krop, Ian E.

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 598 KB

english, 2016

16

CDK4/6 Inhibition in Breast Cancer: Mechanisms of Response and Treatment Failure

Garrido-Castro, Ana C., Goel, Shom

Journal:

Current Breast Cancer Reports

Year:

2017

Language:

english

File:

PDF, 499 KB

english, 2017

17

Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers

Hydbring, Per, Wang, Yinan, Fassl, Anne, Li, Xiaoting, Matia, Veronica, Otto, Tobias, Choi, Yoon Jong, Sweeney, Katharine E., Suski, Jan M., Yin, Hao, Bogorad, Roman L., Goel, Shom, Yuzugullu, Haluk,

Journal:

Year:

2017

Language:

english

File:

PDF, 5.17 MB

english, 2017

18

The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation

Kodack, David P., Askoxylakis, Vasileios, Ferraro, Gino B., Sheng, Qing, Badeaux, Mark, Goel, Shom, Qi, Xiaolong, Shankaraiah, Ram, Cao, Z. Alexander, Ramjiawan, Rakesh R., Bezwada, Divya, Patel, Bhus

Journal:

Science Translational Medicine

Year:

2017

Language:

english

File:

PDF, 1.85 MB

english, 2017

19

Targeting vascular endothelial-cadherin in tumor-associated blood vessels promotes T cell-mediated immunotherapy

Zhao, Yang, Ting, Kaka, Li, Jia, Cogger, Victoria C, Chen, Jinbiao, Johansson-Percival, Anna, Ngiow, Shin Foong, Holst, Jeff, Grau, Georges E. R., Goel, Shom, Moller, Thorleif, Dejana, Elisabetta, McC

Journal:

Cancer Research

Year:

2017

File:

PDF, 3.37 MB

2017

20

CDK4/6 inhibition triggers anti-tumour immunity

Goel, Shom, DeCristo, Molly J., Watt, April C., BrinJones, Haley, Sceneay, Jaclyn, Li, Ben B., Khan, Naveed, Ubellacker, Jessalyn M., Xie, Shaozhen, Metzger-Filho, Otto, Hoog, Jeremy, Ellis, Matthew J

Journal:

Year:

2017

Language:

english

File:

PDF, 8.34 MB

english, 2017

21

CDK4/6 inhibition in breast cancer: current practice and future directions

Pernas, Sonia, Tolaney, Sara M., Winer, Eric P., Goel, Shom

Journal:

Therapeutic Advances in Medical Oncology

Year:

2018

Language:

english

File:

PDF, 422 KB

english, 2018

22

CDK4/6 Inhibition in Cancer: Beyond Cell Cycle Arrest

Goel, Shom, DeCristo, Molly J., McAllister, Sandra S., Zhao, Jean J.

Journal:

Trends in Cell Biology

Year:

2018

Language:

english

File:

PDF, 2.50 MB

english, 2018

23

Ribociclib Plus Trastuzumab in Advanced HER2-Positive Breast Cancer: Results of a Phase 1b/2 Trial

Goel, Shom, Pernas, Sonia, Tan-Wasielewski, Zhenying, Barry, William T., Bardia, Aditya, Rees, Rebecca, Andrews, Chelsea, Tahara, Rie Kawabori, Trippa, Lorenzo, Mayer, Erica L., Winer, Eric P., Spring

Journal:

Clinical Breast Cancer

Year:

2019

Language:

english

File:

PDF, 257 KB

english, 2019

24

CDK4/6 inhibitors in breast cancer: a role in triple-negative disease?

Goel, Shom, Tolaney, Sara M

Journal:

The Lancet Oncology

Year:

2019

Language:

english

File:

PDF, 138 KB

english, 2019

25

CDK4/6 inhibitors in breast cancer: a role in triple-negative disease?

Goel, Shom, Tolaney, Sara M

Journal:

The Lancet Oncology

Year:

2019

File:

PDF, 138 KB

2019

26

Ovarian suppression for adjuvant treatment of hormone receptor-positive early breast cancer

Bui, Kim Tam, Willson, Melina L, Goel, Shom, Beith, Jane, Goodwin, Annabel

Journal:

Cochrane database of systematic reviews

Year:

2020

File:

PDF, 1020 KB

2020

27

Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with hormone receptor-positive, HER2-positive advanced breast cancer (monarcHER): a randomised, open-label, phase 2 trial

Tolaney, Sara M, Wardley, Andrew M, Zambelli, Stefania, Hilton, John F, Troso-Sandoval, Tiffany A, Ricci, Francesco, Im, Seock-Ah, Kim, Sung-Bae, Johnston, Stephen RD, Chan, Arlene, Goel, Shom, Catron

Journal:

The Lancet Oncology

Year:

2020

File:

PDF, 783 KB

2020

28

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Kos, Zuzana, Roblin, Elvire, Kim, Rim S., Michiels, Stefan, Gallas, Brandon D., Chen, Weijie, van de Vijver, Koen K., Goel, Shom, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O.,

Journal:

npj Breast Cancer

Year:

2020

File:

PDF, 6.17 MB

2020

29

Trastuzumab-related cardiotoxicity: what do we know in 2020?

Liu, Jia, Goel, Shom, Beith, Jane McNeil

Journal:

Translational Cancer Research

Year:

2020

File:

PDF, 135 KB

2020

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